By K. Lissák

ISBN-10: 0080107958

ISBN-13: 9780080107950

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It seems that the metabolism of progesterone and its derivatives con- 50 THE NEUROENDOCRINE CONTROL OF ADAPTATION siderably differs from species to species: this problem requires further investigation. A better understanding of pathological processes has been reached in recent years through the study of the adrenocortical secretion of androgens and derivatives of progesterone. The observation that a great number of androgens are secreted in congenital adrenal virilism suggests the possibility that a significant increase in the secretion of 21-desoxysteroids may be a primary pathogenic factor (Jailer, Gold, Wiele and Liebermann, 1955).

1954)* 1-2-14 : 1 Endröczi, Medgyesi and Lissák (1958) 4-6 : 1 Bush (1953) 1-2-7 : 1 Endröczi, Bata and Martin (1958) Rabbit 005 : 1 Bush (1953) Rat 001 : 1 Dog Cat Bush (1953) Endröczi (1957) Weisz et al. (1958) Reif, Longwell (1958) Fox 7 : 1 * in Dorfman (1961) Endröczi (1958) 32 THE N E U R O E N D O C R I N E CONTROL OF A D A P T A T I O N tant components in secretory processes, are not secreted into the blood by the adrenal cortex alone. Although this assumption still lacks experimental proof, it is important to note that the output of these derivatives is significant only under special conditions.

TEKERES, M . and FENDLER, K . : Unpublished data, 1 9 5 8 . ENDRÖCZI, E . and LISSÁK, K . : Acta physiol. Acad. Sei. hung. 15, 2 5 ( 1 9 5 9 ) . ENDRÖCZI, E . and LISSÁK, K . : Probl. Éndokr. Gormonoter. 4 , 1 8 ( 1 9 6 1 ) . ENDRÖCZI, E . and MARTIN, J . : Report on Ann. Meeting Debrecen of Hung. Physiol. Soc, (1958). ENDRÖCZI, E . , TELEGDY, G . and BATA, G . : Acta physiol. Acad. Sei. hung. 14, 3 1 1 (1958). ENDRÖCZI, E . and YANG, T . L . : Acta physiol. Acad. Sei. hung. 18, 1 2 6 ( 1 9 6 0 ) .

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The Neuroendocrine Control of Adaptation by K. Lissák

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