By E. Edmund Kim, David J. Yang (auth.), E. Edmund Kim MD, David J. Yang PhD (eds.)

ISBN-10: 1475735057

ISBN-13: 9781475735055

ISBN-10: 1475735073

ISBN-13: 9781475735079

Cancer cells dedifferentiate with repect to mobilephone functionality; their vascularity is extra leaky, yet perfusion is heterogenerously lowered, and interstitial fluid strain is excessive, significantly retarding supply of brokers from the blood. specified imaging is designed to provide a detectable distinction among tissue that's visualized with unmarried photon and positron emission tomography, magnetic resonance imaging, computed tomography, or ultrasonography. This e-book uniquely studies options for the appliance of molecular specific imaging brokers similar to antibodies, peptides, receptors and distinction brokers within the biologic grading of tumors, differential analysis of tumors, prediction of healing reaction and tracking tumor reaction to therapy. This ebook additionally describes up to date information regarding the imaging of tumor angiogenesis, hypoxia, apoptosis and gene supply in addition to expression within the realizing and application of tumor molecular biology for greater melanoma management.

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Extra info for Targeted Molecular Imaging in Oncology

Example text

The collimator is useful for imaging a large object with a smaller camera. The converging collimator is just the opposite of a diverging collimator. A converging collimator magnifies the object and allows the full utilization of a camera's detection surface for imaging a smaller object to improve the visualization of small structures. For parallel, diverging, and converging collimators, the imaging resolution improves as the source is dose to the collimators. Therefore, to obtain the best possible image resolution, the object should be brought as dose to the collimator as physically allowed.

3. Negendank WG, Brown TR, Evelhock JL. Proceedings of a National Cancer Institute Workshop: MR spectroscopy and tumor cell biology. Radiology 1992;185:875-883. 4. Folkman J, Merler E, Abernathy C, Williams G. Isolation of a tumor factor responsible for angiogenesis. J Exp Med 1971;133:275-288. 5. Steckel R, Kagan AR. Pitfalls in the diagnosis of metastatic disease or local tumor extension with modern imaging techniques. luvest Radiol 1990; 25:818-824. 6. Wood BP. Decision making in radiology. Radiology 1999;211:601-603.

Directions in radiology for the next millennium. AJR 1998;171:1459-1462. 3 Principles of Single Photon Emission Computed Tomography and Positron Emission Tomography Wai-Hoi "Gary" Wong and Jorge Uribe Radionuclide-tracer targeted imaging is based on the detection of gamma rays emitted by the radionuclides embedded in biologically specific compounds after the injection of the compounds into human or experimental animals. The most common imaging radionuclides used for imaging emit gamma rays, which are uncorrelated, and these gamma rays are detected individually or singularly for imaging; this is called single photon imaging.

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Targeted Molecular Imaging in Oncology by E. Edmund Kim, David J. Yang (auth.), E. Edmund Kim MD, David J. Yang PhD (eds.)

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