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Extra resources for Risk to the Thyroid from Ionizing Radiation
For almost two decades, Winship periodically updated his reviews of his own experience and the world’s literature. His 1970 paper summarizes the findings in 856 cases (under the age of 15 y) from 35 countries (Winship and Rosvoll, 1970). Eighty percent of the cases were from the United States. Seventy-three percent of cases had a history of prior radiation therapy for a benign condition such as an “enlarged thymus gland,” chronic tonsillitis, acne, cervical adenitis and angiomas, or nevi of the neck.
2002). , 1997; 1999). 2 DISEASES OF THE THYROID AND PARATHYROID GLANDS / 49 cancers (UNSCEAR, 2000a). , 1994). 3 Functional Diseases Functional abnormalities of the thyroid are characterized as either hyperthyroidism or hypothyroidism. , thyroid enlargement) often accompany these functional abnormalities, diagnosis is usually based on detection of abnormal levels of thyroid hormone in the blood, and treatment is directed at returning these thyroid hormone levels to the normal range. The residual structural abnormalities rarely cause clinicallysignificant symptoms.
In their seminal paper, Duffy and Fitzgerald (1950b) described 28 cases of thyroid cancer in children between age 4 and 18 y. Ten of these children had a history of thymic irradiation. At the time, childhood thyroid cancer was thought to be extremely rare with only ~40 cases having been reported in the English-language literature from 1920 to 1940. Some contemporary authors (McClellan and Francis, 1996) stated that Duffy and Fitzgerald were the first to show that ionizing radiation caused thyroid cancer.
Risk to the Thyroid from Ionizing Radiation by Ncrp Publications