By Paul Tofts

ISBN-10: 0470847212

ISBN-13: 9780470847213

ISBN-10: 0470869526

ISBN-13: 9780470869529

(Radiology category)

"This is a thrilling e-book, with a brand new method of use of the MRI scanner. It bridges the space among medical examine and normal neuro-radiological perform. it truly is obtainable to the scientific radiologist, and but thorough in its therapy of the underlying physics and of the technology of dimension. it truly is more likely to develop into a classic." British scientific Association

This imperative 'how to' handbook of quantitative MR is key for an individual who desires to use the gamut of recent quantitative tips on how to degree the consequences of neurological illness, its development, and its reaction to remedy. It contains both the technique and medical purposes, reflecting the expanding curiosity in quantitative MR in learning affliction and its development.

  • The editor is an MR scientist with a global popularity for top of the range learn
  • The contributions are written together by way of MR physicists and MR clinicians, generating a pragmatic publication for either the study and scientific groups
  • A sensible ebook for either the learn and scientific groups

"Paul Tofts has succeeded brilliantly in shooting the essence of what must develop into the way forward for radiology specifically, and drugs as a rule - quantitative measurements of disease." Robert I. Grossman, M.D. ny, college institution of drugs (from the Foreword)

Chapter 1 suggestions: size and MR (pages 1–15): Paul S. Tofts
Chapter 2 The dimension method: MR info assortment and snapshot research (pages 17–54): Paul S. Tofts
Chapter three QA: caliber insurance, Accuracy, Precision and Phantoms (pages 55–81): Paul S. Tofts
Chapter four PD: Proton Density of Tissue Water (pages 83–109): Paul S. Tofts
Chapter five T1: The Longitudinal leisure Time (pages 111–141): Penny A. Gowland and Valerie L. Stevenson
Chapter 6 T2: The Transverse rest Time (pages 143–201): Philip A. Boulby and Fergus J. Rugg–Gunn
Chapter 7 D: The Diffusion of Water (pages 203–256): Claudia A.M. Wheeler?Kingshott, Gareth J. Barker, Stefan C. A. Steens and Mark A. van Buchem
Chapter eight MT: Magnetization move (pages 257–298): Paul S. Tofts, Stefan C. A. Steens and Mark A. van Buchem
Chapter nine Spectroscopy: 1H Metabolite Concentrations (pages 299–339): Paul S. Tofts and Adam D. Waldman
Chapter 10 T1?W DCE?MRI: T1?Weighted Dynamic Contrast?Enhanced MRI (pages 341–364): Geoff J. M. Parker and Anwar R. Padhani
Chapter eleven T2? and T2*?W DCE?MRI: Blood Perfusion and quantity Estimation utilizing Bolus monitoring (pages 365–412): Richard P. Kennan and H. Rolf Jager
Chapter 12 useful MRI (pages 413–453): Peter Jezzard and Nick F. Ramsey
Chapter thirteen ASL: Blood Perfusion Measurements utilizing Arterial Spin Labelling (pages 455–473): Laura M. Parkes and John A. Detre
Chapter 14 Biology: the importance of MR Parameters in a number of Sclerosis (pages 475–499): Bruno Brochet, Klaus G. Petry and Vincent Dousset
Chapter 15 Spatial Registration of pictures (pages 501–531): John Ashburner and Catriona D. Good
Chapter sixteen quantity and Atrophy (pages 533–558): Geoff J. M. Parker and Declan T. Chard
Chapter 17 form and Texture (pages 559–579): William R. Crum
Chapter 18 Histograms: Measuring sophisticated Diffuse sickness (pages 581–610): Paul S. Tofts, Gerard R. Davies and Jamshid Dehmeshki
Chapter 19 the way forward for qMR: Conclusions and hypothesis (pages 611–617): Paul S. Tofts

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Additional info for Quantitative MRI of the Brain: Measuring Changes Caused by Disease

Example text

These are grouped into the processes of data collection, data analysis and quality assurance, all of which crucially affect how well MR quantities can be measured. g. g. 1. M. W. R. Thompson, Sequence Design R. Venkatesan Principles of Nuclear Paul T. W. A. J. R. Prince Magnetic Resonance Imaging David D. Stark, William G. Bradley Functional MRI Peter Jezzard (Editor), Paul M. Matthews (Editor), Stephen M. Smith (Editor) Barr’s The Human Nervous John A. Kiernan System Date published Number of pages Description 1999 914 Thorough exposition of MRI principles 1993 510 2002 350 Excellent description of principles of NMR and imaging.

Edited by Paul Tofts  2003 John Wiley & Sons, Ltd ISBN: 0-470-84721-2 18 the amount of movement that took place is available as output from the program. Research on why some subjects move, and on what limits how long a subject can stay in the scanner, would improve the quality of MR data that can be obtained. In the future, it may be possible to use fast imaging to dynamically alter the slice positions, tracking the movement of a subject in real time (although movement to a location of different static or RF field value would require some sophisticated correction).

E. 2 mm, which has the same volume (and hence signal-to-noise ratio, for a given imaging time), but is more likely to resolve small structures. e. have the same dimensions in all three directions). Structures in the brain are morphologically very complex; thus a voxel with dimensions 1–10 mm cannot capture this fine detail, and very often there are two (or more) types of tissue inside the voxel. The resulting NMR signal from this voxel is simply a combination, or weighted average, of what each individual tissue would give if it filled the whole voxel.

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Quantitative MRI of the Brain: Measuring Changes Caused by Disease by Paul Tofts

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