By Gian F. Baronzio, E. Dieter Hager

ISBN-10: 0387334408

ISBN-13: 9780387334400

Following an introductory evaluation, Hyperthermia In melanoma therapy: A Primer comprehensively describes the organic purposes for associating hyperthermia with radiation and chemotherapy and the organic and scientific results of hyperthermia on cancerous and basic tissues. The volume’s 20 chapters are prepared in 3 imperative elements: actual and methodological experiences, biologic rules, and medical experiences.

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Extra resources for Hyperthermia In Cancer Treatment: A Primer (Medical Intelligence Unit)

Sample text

4). Phase changes were calculating by subtracting images acquired during heating from a reference image acquired immediately prior to heating. Another step to apply is the correction for phase drift by measuring phase change across an unheated region of the tissue over time (Fig. 5). Ultrasounds Ultrasound is another technology utilised to measure temperature non-invasively. Many studies have been conducted in the last 20 years in this way because it is non-invasive and its cost is low. Thermometry: Clinical Aspects and Perspectives 25 RF nil""— itf^: m Slice SeiectJ Readout i/ — i^ Phase Encode -TR- Echo Echo delayed -TEeff Figure 4.

If we apply the temperature as a characteristic feature of volume, than every sub-volume has the same temperature, and the volume is characterized in quasi-equilibrium. In most of the real cases we pump heat (energy) into the targeted system to change its chemical bonds and reactions. This is the case by the hyperthermia as well; our definite aim is to destroy the malignant cells/tissue. If the energy transfer is correct, than all the pumped in energy is devoted to make this job: changes the chemical bonds and destroys the actual biochemical processes in malignant tissue.

At the clinical results the technical differences are ignored, therefore subjective comparison gains ground. In most of 30 Hyperthermia in Cancer Treatment: A Primer the hyperthermia pubUcations the temperature and the heat as the definite concepts are equally and interchangeably used. By the definition, hyperthermia has to have a heating dose, which is, in most of the medical practices, immediately identified by the temperature. Furthermore, the missing consensus in the explanation of the underlying mechanisms hampers perspicacity.

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Hyperthermia In Cancer Treatment: A Primer (Medical Intelligence Unit) by Gian F. Baronzio, E. Dieter Hager


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