By Barry Barnes

ISBN-10: 0226172953

ISBN-13: 9780226172958

The declaration in 2003 that the Human Genome undertaking had accomplished its map of the whole human genome used to be heralded as a beautiful medical step forward: our first complete photo of the fundamental construction blocks of human existence. because then, boasts concerning the benefits—and warnings of the dangers—of genomics have remained front-page information, with all people agreeing that genomics has the aptitude to greatly modify existence as we all know it.
For the nonscientist, the claims and counterclaims are dizzying—what does it relatively suggest to appreciate the genome? Barry Barnes and John Dupré provide a solution to that question and lots more and plenty extra in Genomes and What to Make of Them, a transparent and full of life account of the genomic revolution and its promise. The publication opens with a short historical past of the technology of genetics and genomics, from Mendel to Watson and Crick and all of the approach as much as Craig Venter; from there the authors delve into using genomics in opting for evolutionary paths—and what it could let us know, for instance, approximately how a ways we actually have come from our ape ancestors. Barnes and Dupré then reflect on either the facility and dangers of genetics, from the industrial power of plant genomes to overblown claims that convinced human genes will be at once tied to such characteristics as intelligence or homosexuality. finally, the authors argue, we're now residing with a brand new wisdom as strong in its manner as nuclear physics­, and the stark offerings that face us—between organic battle and gene remedy, a brand new eugenics or a brand new agricultural revolution—will call for the entire engagement of either scientists and citizens. 

Written in undemanding language yet with no denying the complexity of the problems, Genomes and What to Make of Them is either an up to date primer and a blueprint for the future.

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Extra resources for Genomes and What to Make of Them

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We assume that this difference traces to alleles P and W, which produce the purple and white phenotypes. If these are the only available alleles, any plant will either 4 For an excellent account of this classic work on Drosophila, see Kohler (1994). ONE 26 have two P’s, two W’s, or one of each. We refer to these as the genotypes PP, WW, and PW. What the first law amounts to is the claim that in reproduction either allele is equally likely to be passed to a descendant. The alleles segregate in reproduction: a plant with genotype PW is equally likely to transmit the P and the W genotype.

Molecular biology and molecular genetics began their remarkable expansion, and the helix became an emblem of the molecular approach that continues its remarkable success today, notably in the guise of genomics. The old Mendelian genetics elicits amazement through what it achieved with a limited and slowly changing technology. Industry and organization, plus the astute choice of organisms and experimental systems, had made the very most of what could be absorbed via the eye alone or through the light microscope.

If these are the only available alleles, any plant will either 4 For an excellent account of this classic work on Drosophila, see Kohler (1994). ONE 26 have two P’s, two W’s, or one of each. We refer to these as the genotypes PP, WW, and PW. What the first law amounts to is the claim that in reproduction either allele is equally likely to be passed to a descendant. The alleles segregate in reproduction: a plant with genotype PW is equally likely to transmit the P and the W genotype. The second law states that all genes segregate independently of one another.

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Genomes and What to Make of Them by Barry Barnes


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