By Peter B. Barker, Alberto Bizzi, Nicola De Stefano, Rao Gullapalli, Doris D. M. Lin

ISBN-10: 0511770642

ISBN-13: 9780511770647

ISBN-10: 052186898X

ISBN-13: 9780521868983

In vivo magnetic resonance spectrosopy (MRS) is more and more getting used within the scientific environment, really for neurological issues. scientific MR Spectroscopy - strategies and purposes explains either the underlying actual ideas of MRS and offers a perceptive overview of medical MRS functions. themes lined contain an advent to MRS physics, info content material of spectra from diverse organ platforms, spectral research tools, instructed protocols and localization innovations, and common age- and region-related spectral adaptations within the mind. scientific purposes within the mind are mentioned for mind tumors, hypoxic and ischemic damage, infectious, inflammatory and demyelinating illnesses, epilepsy, neurodegenerative problems, trauma and metabolic ailments. open air of the mind, suggestions and functions are mentioned for MRS within the musculosketal method, breast and prostate. Written through top MRS specialists, this is often a useful consultant for a person drawn to in vivo MRS, together with radiologists, neurologists, neurosurgeons, oncologists and scientific researchers.

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Extra resources for Clinical MR Spectroscopy: Techniques and Applications

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5 T, TE 35 msec) from a phantom without and (top) with eddy current correction. (C) Localized proton spectra of the normal brain with (red) and without (blue) residual water-suppression using a high-pass band-reject filter. (D) A simulated lactate doublet (7 Hz coupling, T2* 100 ms, linewidth ~ 3 Hz) digitized with 512 data points at a rate of 2 kHz. Without zerofilling, the spectral digital resolution is approximately 4 Hz per point, and the doublet structure is not visible. Zero-filling by a factor of 2 allows the doublet to be visualized, and by a factor of 4 or 8 gives the doublet a smoother appearance.

48] Star-Lack J, Vigneron DB, Pauly J, Kurhanewicz J, Nelson SJ. Improved solvent suppression and increased spatial excitation bandwidths for three-dimensional PRESS CSI using phase-compensating spectral/spatial spin-echo pulses. J Magn Reson Imaging 1997; 7: 745–57. [49] Rothman DL, Petroff OA, Behar KL, Mattson RH. Localized 1 H NMR measurements of gammaaminobutyric acid in human brain in vivo. Proc Natl Acad Sci USA 1993; 90: 5662–6. [50] Trabesinger AH, Boesiger P. Improved selectivity of double quantum coherence filtering for the detection of glutathione in the human brain in vivo.

24] Ebel A, Maudsley AA. Improved spectral quality for 3D MR spectroscopic imaging using a high spatial resolution acquisition strategy. Magn Reson Imaging 2003; 21: 113–20. [32] Pruessmann KP, Weiger M, Scheidegger MB, Boesiger P. SENSE: Sensitivity Encoding for fast MRI. Magn Reson Med 1999; 42: 952–62. [33] Sodickson DK, Manning WJ. Simultaneous acquisition of spatial harmonics (SMASH): fast imaging with radiofrequency coil arrays. Magn Reson Med 1997; 38: 591–603. [34] Jakob PM, Griswold MA, Edelman RR, Sodickson DK.

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Clinical MR Spectroscopy: Techniques and Applications by Peter B. Barker, Alberto Bizzi, Nicola De Stefano, Rao Gullapalli, Doris D. M. Lin


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