By Kevin K. W. Wang, Zhiqun Zhang, Firas H. Kobeissy

ISBN-10: 1482239825

ISBN-13: 9781482239829

This ebook explores the new advances within the suggestions and structures utilized in biomarker examine that experience revolutionized the way in which we examine, diagnose, and deal with mind damage stipulations. The participants describe diverse biomarker reviews touching on mind damage and different neurological problems and research different versions and applied sciences used to spot those organic markers. The booklet contains findings from "Omics learn" which were applied to decipher and establish such biomarkers. It discusses protein, microRNA, and adjusted gene profiles and reports neurological problems akin to a number of sclerosis, Charcot-Marie-Tooth sickness, and prion and Alzheimer’s disease.

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Additional resources for Biomarkers of Brain Injury and Neurological Disorders

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2012). , 2006). , 2005). , 2013). In the study of Neselius et al. (2012) brain injury was found to trigger the 26 Biomarkers of Brain Injury and Neurological Disorders release of some biomarkers into the CSF including S100B and other proteins. This; however, does not defy the use of S100B as a screening agent due to its high sensitivity. , 2011). , 2010). Yet, it was investigated as a biomarker indicating neuronal damage and a possible predictor of TBI outcome. The levels of NSE were studied in both serum and ventricular CSF.

D. R. D. Hemphill. 2011. Surveillance for traumatic brain injury-related deaths—United States, 1997–2007. MMWR Surveill Summ. 60: 1–32. W. A. Orman. 2010. The epidemiology of traumatic brain injury. J Head Trauma Rehab. 25: 72–80. , G. Crynen, J. Reed, B. Mouzon, A. Bishop, B. Katz, S. Ferguson, J. Phillips, V. Ganapathi, V. Mathura, A. Roses and M. Mullan. 2012. Identification of plasma biomarkers of TBI outcome using proteomic approaches in an APOE mouse model. J Neurotraum. 29: 246–260. , K.

J Appl Physiol. 26: 46–50. L. J. R. Galarneau. 2011. Blast-related mild traumatic brain injury is associated with a decline in self-rated health amongst US military personnel. Injury. N. J. L. Wilterdink. 2012. Traumatic brain injury: Epidemiology, classification, and pathophysiology. B. N. K. Dash. 2008. Biomarkers in the clinical diagnosis and management of traumatic brain injury. Mol Diagn Ther. 12: 345–358. , S. Jost, S. D. Ebert, T. T. Wunderlich and H. Synowitz. 2000. Temporal profile of release of neurobiochemical markers of brain damage after Proteomics and Systems Biology in TBI 33 traumatic brain injury is associated with intracranial pathology as demonstrated in cranial computerized tomography.

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Biomarkers of Brain Injury and Neurological Disorders by Kevin K. W. Wang, Zhiqun Zhang, Firas H. Kobeissy

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