By Wilson G.N., Schroeder B., Woo J.

Those "500 questions, solutions, and rationalization" books are designed to simulate the USA scientific Licensing exam (USMLE) Step 1. every one is authored through knowledgeable within the box and has been reviewed via scholars who've lately handed the examination. As Step 1 is changing into more and more medical in nature, whilst appropriate, medical vignette-style questions requiring a two-step reasoning technique also are integrated. the entire Pretest titles comprise a "high-yield" truth part to augment key thoughts.

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Extra resources for Biochemistry and Genetics: Pretest Self-Assessment and Review

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It synthesizes 5S ribosomal RNA d. It synthesizes 60S and 40S ribosomal subunits e. It synthesizes all ribosomal RNA primary transcripts 48. Which one of the following statements correctly describes the synthesis of mammalian messenger RNA (mRNA)? a. Each mRNA often encodes several different proteins b. Several different genes may produce identical mRNA molecules c. There is colinearity of the RNA sequence transcribed from a gene and the amino acid sequence of its encoded protein d. The RNA sequence transcribed from a gene is virtually identical to the mRNA that exits from nucleus to cytoplasm e.

C. d. e. Cleave signal sequences Detect cytosolic proteins Direct the signal sequences to ribosomes Bind ribosomes to endoplasmic reticulum Bind mRNA to ribosomes 61. Which of the following statements about ribosomes is true? a. They are an integral part of transcription b. They are found both free in the cytoplasm and bound to membranes c. They are bound together so tightly they cannot dissociate under physiologic conditions d. They are composed of RNA, DNA, and protein e. They are composed of three subunits of unequal size 62.

This binding of the release factor activates peptidyl transferase to hydrolyze the bond between the polypeptide and the tRNA occupying the P site. Thus, instead of forming a peptide bond, peptidyl transferase catalyzes the hydrolytic step that leads to the release of newly synthesized proteins. Following release of the polypeptide, the ribosome dissociates into its major subunits. 60. The answer is d. (Murray, pp 452–467. Scriver, pp 3–45. Sack, pp 1–40. ) The directing of nascent polypeptide chains to the endoplasmic reticulum is regulated by signal recognition particles (SRPs).

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Biochemistry and Genetics: Pretest Self-Assessment and Review by Wilson G.N., Schroeder B., Woo J.


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