By David Rollinson, S.I. Hay

ISBN-10: 0123742293

ISBN-13: 9780123742292

First released in 1963, Advances in Parasitology includes finished and up to date studies in all parts of curiosity in modern parasitology. Advances in Parasitology comprises clinical reports on parasites of significant impact, resembling Plasmodium falciparum and trypanosomes. The sequence additionally comprises studies of extra conventional components, reminiscent of zoology, taxonomy, and existence heritage, which form present considering and purposes. Eclectic volumes are supplemented through thematic volumes on quite a few issues together with distant Sensing and Geographical info platforms in Epidemiology and The Evolution of Parasitism--A phylogenetic persepective.

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Example text

Falciparum genome. It is plausible that heterologous/homologous immunity to P. falciparum is explained by different msp or var gene families and their patterns of crossimmunity. Human immune response may also be heterogeneous, in that the state of clinical immunity in different humans could be conferred by immunity to different sets of immunogens. Continual sexual reassortment of the genes for merozoite-stage proteins and the var genes during meiosis in the mosquito, and strong disruptive selection provide new variation.

Vivax and our A. maculopennis is a very efficient carrier of P. ovale’ (Shute, 1940). In the United States, extensive transmission experiments with indigenous species of Anopheles and ‘exotic’ strains of P. vivax and P. g. , 1947). A particular concern was that ‘returning soldiers with such infections may be responsible for the establishment in this country of epidemic or endemic foci for imported vivax strains’ (Watson, 1945). Extensive studies of P. vivax infections from the ‘Solomon Islands, New Hebrides islands, New Guinea, Tunisia, Liberia, Trinidad, and the China-Burma-India theater’ with the major malaria vectors of the Western 14 F.

At higher levels of endemicity the number of strains prevalent may be expected to be greater [and] through repeated reinoculations in the course of time with other strains, the individual’s immunity will become polyvalent to all of the species and strains of parasites which are locally prevalent . . A person may be reinoculated one or more times with the same or a different species or strain of parasite, after an interval which should be expected to vary with the endemic or epidemic level prevailing .

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Advances in Parasitology, Vol. 66 by David Rollinson, S.I. Hay

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